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Natural selection retains overrepresented out-of-frame stop codons against frameshift peptides in prokaryotes
BACKGROUND: Out-of-frame stop codons (OSCs) occur naturally in coding sequences of all organisms, providing a mechanism of early termination of translation in incorrect reading frame so that the metabolic cost associated with frameshift events can be reduced. Given such a functional significance, we...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996987/ https://ncbi.nlm.nih.gov/pubmed/20828396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-491 |
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