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Functional analysis of the stem loop S3 and S4 structures in the coronavirus 3′UTR
We designed a series of mutations to separately destabilize two helical stems (designated S3 and S4) predicted by a covariation-based model of the coronavirus 3′UTR (Zust et al., 2008). Mouse hepatitis virus genomes containing three or four nucleotide mutations that destabilize either S3 or S4 were...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700632/ https://ncbi.nlm.nih.gov/pubmed/23683838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.04.021 |
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