Mouse Hepatitis Virus Stem-Loop 4 Functions as a Spacer Element Required To Drive Subgenomic RNA Synthesis

The 5′ 140 nucleotides of the mouse hepatitis virus (MHV) 5′ untranslated region (5′UTR) are predicted to contain three secondary structures, stem-loop 1 (SL1), SL2, and SL4. SL1 and SL2 are required for subgenomic RNA synthesis. The current study focuses on SL4, which contains two base-paired regio...

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Detalhes bibliográficos
Main Authors: Yang, Dong, Liu, Pinghua, Giedroc, David P., Leibowitz, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165806/
https://ncbi.nlm.nih.gov/pubmed/21715502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05092-11
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