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Polydopamine-based surface modification for the development of peritumorally activatable nanoparticles

PURPOSE: To create a poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs), where a drug-encapsulating NP core is covered with polyethylene glycol (PEG) in a normal condition but exposes a cell-interactive TAT-modified surface in an environment rich in matrix metalloproteinases (MMPs). METHODS: P...

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Main Authors: Gullotti, Emily, Park, Joonyoung, Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700573/
https://ncbi.nlm.nih.gov/pubmed/23609560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1039-y
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