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Beyond the imaging: Limitations of cellular uptake study in the evaluation of nanoparticles

Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) conjugated to a cell-penetrating peptide, TAT, was used to increase intracellular delivery of paclitaxel (PTX) to multi-drug resistant (MDR) cells. Efficient cellular uptake of the TAT-conjugated PLGA NPs was observed; however, it did not tran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gullotti, Emily, Yeo, Yoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447109/
https://ncbi.nlm.nih.gov/pubmed/22568932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.04.042
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