Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties

Interleukin-27 (IL-27) is a pleiotropic cytokine which plays important and diverse roles in the immune system. We have previously demonstrated that IL-27 induces potent anti-viral effects against HIV-1, HIV-2, SIV, HSV-2, KSHV and influenza viruses in macrophages. This induction occurred in an Inter...

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Hauptverfasser: Swaminathan, Sanjay, Hu, Xiaojun, Zheng, Xin, Kriga, Yuliya, Shetty, Jyoti, Zhao, Yongmei, Stephens, Robert, Tran, Bao, Baseler, Michael W., Yang, Jun, Lempicki, Richard A., Huang, Dawei, Lane, H. Clifford, Imamichi, Tomozumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700531/
https://ncbi.nlm.nih.gov/pubmed/23535375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.046
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