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Accurate high-throughput structure mapping and prediction with transition metal ion FRET

Mapping the landscape of a protein’s conformational space is essential to understanding its functions and regulation. The limitations of many structural methods have made this process challenging for most proteins. Here, we report that transition metal ion FRET (tmFRET) can be used in a rapid, highl...

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Detalhes bibliográficos
Main Authors: Yu, Xiaozhen, Wu, Xiongwu, Bermejo, Guillermo A., Brooks, Bernard R., Taraska, Justin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700372/
https://ncbi.nlm.nih.gov/pubmed/23273426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.11.013
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