A Combination of DR5 Agonistic Monoclonal Antibody with Gemcitabine Targets Pancreatic Cancer Stem Cells and Results in Long-term Disease Control in Human Pancreatic Cancer Model

Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy with one of the worst outcomes among all cancers. PDA often recurs after initial treatment to result in patient death despite the use of chemotherapy or radiation therapy. PDA contains a subset of tumor-initiating cells capable of ex...

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Bibliografiske detaljer
Main Authors: Rajeshkumar, N.V., Rasheed, Zeshaan A., García-García, Elena, López-Ríos, Fernando, Fujiwara, Kosaku, Matsui, William H., Hidalgo, Manuel
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700345/
https://ncbi.nlm.nih.gov/pubmed/20660600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0370
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