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PET with (64)Cu–Histidine for Noninvasive Diagnosis of Biliary Copper Excretion in Long–Evans Cinnamon Rat Model of Wilson Disease
Excretion of copper into bile requires the copper transporter Atp7b, which is deficient in Wilson disease. We hypothesized that a radiocopper–histidine complex would be effective for diagnosing Wilson disease by molecular imaging and tested this hypothesis in the Long–Evans cinnamon (LEC) rat model...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700334/ https://ncbi.nlm.nih.gov/pubmed/22577234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.092361 |
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