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PET with (64)Cu–Histidine for Noninvasive Diagnosis of Biliary Copper Excretion in Long–Evans Cinnamon Rat Model of Wilson Disease

Excretion of copper into bile requires the copper transporter Atp7b, which is deficient in Wilson disease. We hypothesized that a radiocopper–histidine complex would be effective for diagnosing Wilson disease by molecular imaging and tested this hypothesis in the Long–Evans cinnamon (LEC) rat model...

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Sonraí Bibleagrafaíochta
Main Authors: Bahde, Ralf, Kapoor, Sorabh, Bhargava, Kuldeep K., Schilsky, Michael L., Palestro, Christopher J., Gupta, Sanjeev
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700334/
https://ncbi.nlm.nih.gov/pubmed/22577234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.092361
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