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Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes.

A two-step model to explain the high frequency of mutation at the diploid adenine phosphoribosyltransferase (aprt) locus in CHO cells has been proposed previously (Simon et al., Mol. Cell. Biol. 2:1126-1133, 1982). This model indicates that two distinct classes of aprt heterozygotes can be isolated....

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Publicat a:Mol Cell Biol
Autors principals: Simon, A E, Taylor, M W, Bradley, W E
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6646118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.10.1703-1710.1983
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