Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes.

A two-step model to explain the high frequency of mutation at the diploid adenine phosphoribosyltransferase (aprt) locus in CHO cells has been proposed previously (Simon et al., Mol. Cell. Biol. 2:1126-1133, 1982). This model indicates that two distinct classes of aprt heterozygotes can be isolated....

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Pubblicato in:	Mol Cell Biol
Autori principali:	Simon, A E, Taylor, M W, Bradley, W E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6646118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.10.1703-1710.1983
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