Early Gag Immunodominance of the HIV-Specific T-Cell Response during Acute/Early Infection Is Associated with Higher CD8(+) T-Cell Antiviral Activity and Correlates with Preservation of the CD4(+) T-Cell Compartment

The important role of the CD8(+) T-cell response on HIV control is well established. Moreover, the acute phase of infection represents a proper scenario to delineate the antiviral cellular functions that best correlate with control. Here, multiple functional aspects (specificity, ex vivo viral inhib...

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Detalhes bibliográficos
Main Authors: Turk, Gabriela, Ghiglione, Yanina, Falivene, Juliana, Socias, María Eugenia, Laufer, Natalia, Coloccini, Romina Soledad, Rodriguez, Ana María, Ruiz, María Julia, Pando, María Ángeles, Giavedoni, Luis David, Cahn, Pedro, Sued, Omar, Salomon, Horacio, Gherardi, María Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700299/
https://ncbi.nlm.nih.gov/pubmed/23616666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00865-13
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