Early Skewed Distribution of Total and HIV-Specific CD8(+) T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression

The important role of the CD8(+) T-cells on HIV control is well established. However, correlates of immune protection remain elusive. Although the importance of CD8(+) T-cell specificity and functionality in virus control has been underscored, further unraveling the link between CD8(+) T-cell differ...

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Detalhes bibliográficos
Main Authors: Ghiglione, Yanina, Falivene, Juliana, Ruiz, María Julia, Laufer, Natalia, Socías, María Eugenia, Cahn, Pedro, Giavedoni, Luis, Sued, Omar, Gherardi, María Magdalena, Salomón, Horacio, Turk, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122399/
https://ncbi.nlm.nih.gov/pubmed/25093660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104235
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