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Functional Similarity between E6 Proteins of Cutaneous Human Papillomaviruses and the Adenovirus E1A Tumor-Restraining Module

The adenovirus E1A C-terminal region restrains oncogenic transformation through interaction with three distinct cellular protein complexes that include the DYRK1A/1B/HAN11 complex. The E6 proteins of beta-human papillomaviruses (beta-HPVs) also interact with the DYRK1/HAN11 complex. A variant of HPV...

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Autors principals: Kuppuswamy, Mohan, Subramanian, T., Kostas-Polston, Elizabeth, Vijayalingam, S., Zhao, Ling-jun, Varvares, Mark, Chinnadurai, G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700293/
https://ncbi.nlm.nih.gov/pubmed/23637414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00037-13
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