Adenovirus Type 5 E1A and E6 Proteins of Low-Risk Cutaneous Beta-Human Papillomaviruses Suppress Cell Transformation through Interaction with FOXK1/K2 Transcription Factors

The adenovirus (Adv) oncoprotein E1A stimulates cell proliferation and inhibits differentiation. These activities are primarily linked to the N-terminal region (exon 1) of E1A, which interacts with multiple cellular protein complexes. The C terminus (exon 2) of E1A antagonizes these processes, media...

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Bibliografische gegevens
Hoofdauteurs: Komorek, Jessica, Kuppuswamy, Mohan, Subramanian, T., Vijayalingam, S., Lomonosova, Elena, Zhao, Ling-jun, Mymryk, Joe S., Schmitt, Kimberly, Chinnadurai, G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Transformation and Oncogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826030/
https://ncbi.nlm.nih.gov/pubmed/20053746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02119-09
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