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The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

Ebola virus (EBOV) infections are characterized by deficient T lymphocyte responses, T lymphocyte apoptosis, and lymphopenia in the absence of direct infection of T lymphocytes. In contrast, dendritic cells (DC) are infected but fail to mature appropriately, thereby impairing the T cell response. We...

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Autori principali: Lubaki, Ndongala M., Ilinykh, Philipp, Pietzsch, Colette, Tigabu, Bersabeh, Freiberg, Alexander N., Koup, Richard A., Bukreyev, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700277/
https://ncbi.nlm.nih.gov/pubmed/23616668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03316-12
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