Influence of Mismatch of Env Sequences on Vaccine Protection by Live Attenuated Simian Immunodeficiency Virus

Vaccine/challenge experiments that utilize live attenuated strains of simian immunodeficiency virus (SIV) in monkeys may be useful for elucidating what is needed from a vaccine in order to achieve protective immunity. Derivatives of SIVmac239 and SIVmac239Δnef were constructed in which env sequences...

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Главные авторы: Manrique, Julieta, Piatak, Michael, Lauer, William, Johnson, Welkin, Mansfield, Keith, Lifson, Jeffrey, Desrosiers, Ronald
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700272/
https://ncbi.nlm.nih.gov/pubmed/23637396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00798-13
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