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Polyomavirus-plasmid recombinants capable of replicating have an enhanced transforming potential.

The frequency of transformation of rodent fibroblasts by polyomavirus is enhanced by a viral gene product, large T-antigen. However, this effect of large T-antigen cannot be demonstrated with pBR322-cloned viral DNA. Recently, it was discovered that pBR322 contains cis-acting sequences inhibitory to...

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Publicado en:Mol Cell Biol
Autores principales: Muller, W J, Naujokas, M A, Hassell, J A
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1983
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6314125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.9.1670-1674.1983
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