Polyomavirus-plasmid recombinants capable of replicating have an enhanced transforming potential.
The frequency of transformation of rodent fibroblasts by polyomavirus is enhanced by a viral gene product, large T-antigen. However, this effect of large T-antigen cannot be demonstrated with pBR322-cloned viral DNA. Recently, it was discovered that pBR322 contains cis-acting sequences inhibitory to...
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| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1983
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6314125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.9.1670-1674.1983 |
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