NF-E2 p45 Is Important for Establishing Normal Function of Platelets

NF-E2 is a heterodimeric transcription factor consisting of p45 and small Maf subunits. Since p45(−/−) mice display severe thrombocytopenia, p45 is recognized as a critical regulator of platelet production from megakaryocytes. To identify direct p45 target genes in megakaryocytes, we used chromatin...

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Hauptverfasser: Fujita, Rie, Takayama-Tsujimoto, Mariko, Satoh, Hironori, Gutiérrez, Laura, Aburatani, Hiroyuki, Fujii, Satoshi, Sarai, Akinori, Bresnick, Emery H., Yamamoto, Masayuki, Motohashi, Hozumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700136/
https://ncbi.nlm.nih.gov/pubmed/23648484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01274-12
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