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SAD-A Potentiates Glucose-Stimulated Insulin Secretion as a Mediator of Glucagon-Like Peptide 1 Response in Pancreatic β Cells

Type 2 diabetes is characterized by defective glucose-stimulated insulin secretion (GSIS) from pancreatic β cells, which can be restored by glucagon-like peptide 1 (GLP-1), an incretin hormone commonly used for the treatment of type 2 diabetes. However, molecular mechanisms by which GLP-1 affects gl...

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Detalhes bibliográficos
Main Authors: Nie, Jia, Lilley, Brendan N., Pan, Y. Albert, Faruque, Omar, Liu, Xiaolei, Zhang, Weiping, Sanes, Joshua R., Han, Xiao, Shi, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700116/
https://ncbi.nlm.nih.gov/pubmed/23629625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00285-13
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