Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels

Transcription factor Nrf2 (NF-E2-related factor 2) is essential for oxidative and electrophilic stress responses. While it has been well characterized that Nrf2 activity is tightly regulated at the protein level through proteasomal degradation via Keap1 (Kelch-like ECH-associated protein 1)-mediated...

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Main Authors: Suzuki, Takafumi, Shibata, Tatsuhiro, Takaya, Kai, Shiraishi, Kouya, Kohno, Takashi, Kunitoh, Hideo, Tsuta, Koji, Furuta, Koh, Goto, Koichi, Hosoda, Fumie, Sakamoto, Hiromi, Motohashi, Hozumi, Yamamoto, Masayuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700104/
https://ncbi.nlm.nih.gov/pubmed/23572560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00065-13
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