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Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels

Transcription factor Nrf2 (NF-E2-related factor 2) is essential for oxidative and electrophilic stress responses. While it has been well characterized that Nrf2 activity is tightly regulated at the protein level through proteasomal degradation via Keap1 (Kelch-like ECH-associated protein 1)-mediated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suzuki, Takafumi, Shibata, Tatsuhiro, Takaya, Kai, Shiraishi, Kouya, Kohno, Takashi, Kunitoh, Hideo, Tsuta, Koji, Furuta, Koh, Goto, Koichi, Hosoda, Fumie, Sakamoto, Hiromi, Motohashi, Hozumi, Yamamoto, Masayuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700104/
https://ncbi.nlm.nih.gov/pubmed/23572560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00065-13
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