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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
The lysosomal-autophagic pathway is activated by starvation and plays an important role in both cellular clearance and lipid catabolism. However, the transcriptional regulation of this pathway in response to metabolic cues is currently uncharacterized. Here we show that the transcription factor EB (...
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| Main Authors: | , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699877/ https://ncbi.nlm.nih.gov/pubmed/23604321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2718 |
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