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Differences in metabolic and mitogenic signalling of insulin glargine and insulin aspart B10 in rats
AIMS/HYPOTHESIS: In vitro, insulin glargine (A21Gly,B31Arg,B32Arg human insulin) has an insulin receptor (IR) profile similar to that of human insulin, but a slightly higher affinity for the IGF-1 receptor (IGF1R). Insulin aspart B10 (B10Asp human insulin) (AspB10), the only insulin analogue with pr...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699703/ https://ncbi.nlm.nih.gov/pubmed/23653049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-2923-z |
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