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Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors

The rapidly increasing number of high-resolution X-ray structures of G-protein coupled receptors (GPCRs) creates a unique opportunity to employ comparative modeling and docking to provide valuable insight into the function and ligand binding determinants of novel receptors, to assist in virtual scre...

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Detaylı Bibliyografya
Asıl Yazarlar: Nguyen, Elizabeth Dong, Norn, Christoffer, Frimurer, Thomas M., Meiler, Jens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699586/
https://ncbi.nlm.nih.gov/pubmed/23844000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067302
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