Metabolic engineering of Kluyveromyces lactis for L-ascorbic acid (vitamin C) biosynthesis

BACKGROUND: L-ascorbic acid (L-AA) is naturally synthesized in plants from D-glucose by 10 steps pathway. The pathway branch to synthesize L-galactose, the key intermediate for L-ascorbic acid biosynthesis, has been recently elucidated. Budding yeast produces an 5-carbon ascorbic acid analogue Dehyd...

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Autori principali: Rosa, Júlio César Câmara, Colombo, Lívia Tavares, Alvim, Mariana Caroline Tocantins, Avonce, Nelson, Van Dijck, Patrick, Passos, Flávia Maria Lopes
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699391/
https://ncbi.nlm.nih.gov/pubmed/23799937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-59
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