Stepwise isolation and properties of unstable Chinese hamster cell variants that overproduce adenylate deaminase.
Addition of coformycin (0.5 microgram/ml) to a culture medium containing adenine causes in Chinese hamster fibroblasts a lethal depletion of IMP. Resistant variants have been recovered, some of which exhibit increased adenylate deaminase activity. (Debatisse et al., J. Cell. Physiol., 106:1-11, 1981...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7162515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.11.1346-1353.1982 |
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