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Stepwise isolation and properties of unstable Chinese hamster cell variants that overproduce adenylate deaminase.

Addition of coformycin (0.5 microgram/ml) to a culture medium containing adenine causes in Chinese hamster fibroblasts a lethal depletion of IMP. Resistant variants have been recovered, some of which exhibit increased adenylate deaminase activity. (Debatisse et al., J. Cell. Physiol., 106:1-11, 1981...

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Publicado en:Mol Cell Biol
Autores principales: Debatisse, M, Berry, M, Buttin, G
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1982
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7162515/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.11.1346
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