High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

BACKGROUND: The demand of monospecific high affinity binding reagents, particularly monoclonal antibodies, has been steadily increasing over the last years. Enhanced throughput of antibody generation has been addressed by optimizing in vitro selection using phage display which moved the major bottle...

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Main Authors: Jäger, Volker, Büssow, Konrad, Wagner, Andreas, Weber, Susanne, Hust, Michael, Frenzel, André, Schirrmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699382/
https://ncbi.nlm.nih.gov/pubmed/23802841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-52
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