WNTLESS IS REQUIRED FOR PERIPHERAL LUNG DIFFERENTIATION AND PULMONARY VASCULAR DEVELOPMENT

Wntless (Wls), a gene highly conserved across the animal kingdom, encodes for a transmembrane protein that mediates Wnt ligand secretion. Wls is expressed in developing lung, wherein Wnt signaling is necessary for pulmonary morphogenesis. We hypothesize that Wls plays a critical role in modulating W...

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Autores principales: Cornett, Bridget, Snowball, John, Varisco, Brian M., Lang, Richard, Whitsett, Jeffrey, Sinner, Debora
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699333/
https://ncbi.nlm.nih.gov/pubmed/23523683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.03.010
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