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Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning

Excessive production of pro-inflammatory cytokines in the senescent brain in response to peripheral immune stimulation is thought to induce behavioral pathology, however, few studies have examined if the increase in pro-inflammatory cytokines is accompanied by an increase in cytokine signaling. Here...

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Detalhes bibliográficos
Main Authors: Burton, Michael D., Johnson, Rodney W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699311/
https://ncbi.nlm.nih.gov/pubmed/22062497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2011.10.008
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