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Slowed Dynamics of Thin Filament Regulatory Units Reduces Ca(2+)-Sensitivity of Cardiac Biomechanical Function
Actomyosin kinetics in both skinned skeletal muscle fibers at maximum Ca(2+)-activation and unregulated in vitro motility assays are modulated by solvent microviscosity in a manner consistent with a diffusion limited process. Viscosity might also influence cardiac thin filament Ca(2+)-regulatory pro...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3698987/ https://ncbi.nlm.nih.gov/pubmed/23833690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-013-0269-8 |
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