Genetic Variation in the Lipoxygenase Pathway and Risk of Colorectal Neoplasia

Arachidonate lipoxygenase (ALOX) enzymes metabolize arachidonic acid to generate potent inflammatory mediators and play an important role in inflammation-associated diseases. We investigated associations between colorectal cancer risk and polymorphisms in ALOX5, FLAP, ALOX12, and ALOX15, and their i...

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Main Authors: Kleinstein, Sarah E., Heath, Laura, Makar, Karen W., Poole, Elizabeth M., Seufert, Brenna L., Slattery, Martha L., Xiao, Liren, Duggan, David J., Hsu, Li, Curtin, Karen, Koepl, Lisel, Muehling, Jill, Taverna, Darin, Caan, Bette J., Carlson, Christopher S., Potter, John D., Ulrich, Cornelia M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698944/
https://ncbi.nlm.nih.gov/pubmed/23404351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22042
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