Reduced Neointima Formation After Arterial Injury in CD4−/− Mice Is Mediated by CD8(+)CD28(hi) T Cells

BACKGROUND: CD8(+) T‐cell activation, characterized by increased CD28 expression, reduces neointima formation after arterial injury in mice. The CD8(+)CD28(hi) phenotype is associated with increased effector function. In this study, we used a mouse model that has CD8(+) but no CD4(+) T cells (CD4−/−...

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Bibliografiske detaljer
Main Authors: Dimayuga, Paul C., Chyu, Kuang‐Yuh, Lio, Wai Man, Zhao, Xiaoning, Yano, Juliana, Zhou, Jianchang, Honjo, Tomoyuki, Shah, Prediman K., Cercek, Bojan
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698777/
https://ncbi.nlm.nih.gov/pubmed/23702879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000155
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