Genetic Deletion of Uncoupling Protein 3 Exaggerates Apoptotic Cell Death in the Ischemic Heart Leading to Heart Failure

BACKGROUND: Uncoupling protein 3 (ucp3) is a member of the mitochondrial anion carrier superfamily of proteins uncoupling mitochondrial respiration. In this study, we investigated the effects of ucp3 genetic deletion on mitochondrial function and cell survival under low oxygen conditions in vitro an...

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מידע ביבליוגרפי
Main Authors: Perrino, Cinzia, Schiattarella, Gabriele G., Sannino, Anna, Pironti, Gianluigi, Petretta, Maria Piera, Cannavo, Alessandro, Gargiulo, Giuseppe, Ilardi, Federica, Magliulo, Fabio, Franzone, Anna, Carotenuto, Giuseppe, Serino, Federica, Altobelli, Giovanna G., Cimini, Vincenzo, Cuocolo, Alberto, Lombardi, Assunta, Goglia, Fernando, Indolfi, Ciro, Trimarco, Bruno, Esposito, Giovanni
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2013
נושאים:
Original Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698767/
https://ncbi.nlm.nih.gov/pubmed/23688674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000086
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