Genetic Deletion of Uncoupling Protein 3 Exaggerates Apoptotic Cell Death in the Ischemic Heart Leading to Heart Failure

BACKGROUND: Uncoupling protein 3 (ucp3) is a member of the mitochondrial anion carrier superfamily of proteins uncoupling mitochondrial respiration. In this study, we investigated the effects of ucp3 genetic deletion on mitochondrial function and cell survival under low oxygen conditions in vitro an...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Perrino, Cinzia, Schiattarella, Gabriele G., Sannino, Anna, Pironti, Gianluigi, Petretta, Maria Piera, Cannavo, Alessandro, Gargiulo, Giuseppe, Ilardi, Federica, Magliulo, Fabio, Franzone, Anna, Carotenuto, Giuseppe, Serino, Federica, Altobelli, Giovanna G., Cimini, Vincenzo, Cuocolo, Alberto, Lombardi, Assunta, Goglia, Fernando, Indolfi, Ciro, Trimarco, Bruno, Esposito, Giovanni
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2013
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698767/
https://ncbi.nlm.nih.gov/pubmed/23688674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000086
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires