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Genetic Deletion of Uncoupling Protein 3 Exaggerates Apoptotic Cell Death in the Ischemic Heart Leading to Heart Failure
BACKGROUND: Uncoupling protein 3 (ucp3) is a member of the mitochondrial anion carrier superfamily of proteins uncoupling mitochondrial respiration. In this study, we investigated the effects of ucp3 genetic deletion on mitochondrial function and cell survival under low oxygen conditions in vitro an...
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Glavni autori: | , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Blackwell Publishing Ltd
2013
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3698767/ https://ncbi.nlm.nih.gov/pubmed/23688674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000086 |
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