Genetic Deletion of Uncoupling Protein 3 Exaggerates Apoptotic Cell Death in the Ischemic Heart Leading to Heart Failure

BACKGROUND: Uncoupling protein 3 (ucp3) is a member of the mitochondrial anion carrier superfamily of proteins uncoupling mitochondrial respiration. In this study, we investigated the effects of ucp3 genetic deletion on mitochondrial function and cell survival under low oxygen conditions in vitro an...

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Bibliografische gegevens
Hoofdauteurs: Perrino, Cinzia, Schiattarella, Gabriele G., Sannino, Anna, Pironti, Gianluigi, Petretta, Maria Piera, Cannavo, Alessandro, Gargiulo, Giuseppe, Ilardi, Federica, Magliulo, Fabio, Franzone, Anna, Carotenuto, Giuseppe, Serino, Federica, Altobelli, Giovanna G., Cimini, Vincenzo, Cuocolo, Alberto, Lombardi, Assunta, Goglia, Fernando, Indolfi, Ciro, Trimarco, Bruno, Esposito, Giovanni
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2013
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698767/
https://ncbi.nlm.nih.gov/pubmed/23688674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000086
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