Arachidonic Acid–Induced Dilation in Human Coronary Arterioles: Convergence of Signaling Mechanisms on Endothelial TRPV4‐Mediated Ca(2+) Entry

BACKGROUND: Arachidonic acid (AA) and/or its enzymatic metabolites are important lipid mediators contributing to endothelium‐derived hyperpolarizing factor (EDHF)–mediated dilation in multiple vascular beds, including human coronary arterioles (HCAs). However, the mechanisms of action of these lipid...

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Main Authors: Zheng, Xiaodong, Zinkevich, Natalya S., Gebremedhin, Debebe, Gauthier, Kathryn M., Nishijima, Yoshinori, Fang, Juan, Wilcox, David A., Campbell, William B., Gutterman, David D., Zhang, David X.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698766/
https://ncbi.nlm.nih.gov/pubmed/23619744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000080
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