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An In Vitro Model of Developmental Synaptogenesis Using Cocultures of Human Neural Progenitors and Cochlear Explants

In mammals, the sensory hair cells and auditory neurons do not spontaneously regenerate and their loss results in permanent hearing impairment. Stem cell therapy is one emerging strategy that is being investigated to overcome the loss of sensory cells after hearing loss. To successfully replace audi...

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Bibliographic Details
Main Authors: Nayagam, Bryony A., Edge, Albert S., Needham, Karina, Hyakumura, Tomoko, Leung, Jessie, Nayagam, David A.X., Dottori, Mirella
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698684/
https://ncbi.nlm.nih.gov/pubmed/23078657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0082
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