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Immunoglobulin gene rearrangements in normal mouse B cells.

We have analyzed the structure of rearranged mu heavy-chain genes obtained from the genomic DNA of normal BALB/c mouse spleen cells expressing surface immunoglobulin M. Examples were found of two types of nonproductive rearrangements, which may be responsible for allelic exclusion in normal B cells....

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Early, P, Nottenburg, C, Weissman, I, Hood, L
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1982
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6821506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.7.829-836.1982
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