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Immunoglobulin gene rearrangements in normal mouse B cells.

We have analyzed the structure of rearranged mu heavy-chain genes obtained from the genomic DNA of normal BALB/c mouse spleen cells expressing surface immunoglobulin M. Examples were found of two types of nonproductive rearrangements, which may be responsible for allelic exclusion in normal B cells....

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Detalhes bibliográficos
Main Authors: Early, P, Nottenburg, C, Weissman, I, Hood, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369865/
https://ncbi.nlm.nih.gov/pubmed/6821506
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