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Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

Drugs that kill tuberculosis more quickly could shorten chemotherapy significantly. In Escherichia coli, a common mechanism of cell death by bactericidal antibiotics involves the generation of highly reactive hydroxyl radicals via the Fenton reaction. Here we show that vitamin C, a compound known to...

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Hlavní autoři: Vilchèze, Catherine, Hartman, Travis, Weinrick, Brian, Jacobs, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698613/
https://ncbi.nlm.nih.gov/pubmed/23695675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2898
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