RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes

We previously demonstrated that overexpression of RanBP9 led to enhanced Aβ generation in a variety of cell lines and primary neuronal cultures, and subsequently, we confirmed increased amyloid plaque burden in a mouse model of Alzheimer's disease (AD). In the present study, we found striking r...

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Main Authors: Palavicini, J P, Wang, H, Bianchi, E, Xu, S, Rao, J S, Kang, D E, Lakshmana, M K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698550/
https://ncbi.nlm.nih.gov/pubmed/23764848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.183
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