Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling

Nitric oxide (NO) is a ubiquitous mediator of inflammation and immunity, involved in the pathogenesis and control of infectious diseases, autoimmunity, and cancer. We observed that the expression of nitric oxide synthase-2 (NOS2/iNOS) positively correlates with Th17 responses in patients with ovaria...

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Main Authors: Obermajer, Nataša, Wong, Jeffrey L., Edwards, Robert P., Chen, Kong, Scott, Melanie, Khader, Shabaana, Kolls, Jay K., Odunsi, Kunle, Billiar, Timothy R., Kalinski, Pawel
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698515/
https://ncbi.nlm.nih.gov/pubmed/23797095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121277
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