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Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

Approximately 30 % of colorectal carcinomas develop via the serrated neoplasia pathway characterized by widespread DNA methylation and frequent BRAF mutation. Serrated polyps represent a heterogeneous group of polyps which are the precursor lesions to serrated pathway colorectal carcinomas. The hist...

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Detalhes bibliográficos
Main Authors: Rosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A., Whitehall, Vicki L. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698429/
https://ncbi.nlm.nih.gov/pubmed/23208018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-012-0720-y
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