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T cells interact with T cells via CD40-CD154 to promote autoimmunity in T1D
We have investigated the role of CD40 signaling in islet-reactive, diabetogenic CD4 Th1 T cell clones. Using multispectral flow cytometry, we showed that CD40 and CD154 are co-expressed and form complexes on the surface of activated T cells. We also demonstrate that activated T cells can transactiva...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697870/ https://ncbi.nlm.nih.gov/pubmed/22488364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142071 |
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