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N-acetylcysteine decreased nicotine self-administration and cue-induced reinstatement of nicotine seeking in rats: Comparison with the effects of N-acetylcysteine on food responding and food seeking

RATIONALE: Chronic nicotine administration decreases the functioning of the cystine-glutamate antiporter system x(c)(_) which is hypothesized to promote nicotine-taking and -seeking behaviors. N-acetylcysteine (NAC), a cystine pro-drug, increases the activity of the cystine-glutamate antiporter syst...

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Detalhes bibliográficos
Main Authors: Ramirez-Niño, Ana M., D'Souza, Manoranjan S., Markou, Athina
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697766/
https://ncbi.nlm.nih.gov/pubmed/22903390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2837-3
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