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N-acetylcysteine decreased nicotine self-administration and cue-induced reinstatement of nicotine seeking in rats: Comparison with the effects of N-acetylcysteine on food responding and food seeking
RATIONALE: Chronic nicotine administration decreases the functioning of the cystine-glutamate antiporter system x(c)(_) which is hypothesized to promote nicotine-taking and -seeking behaviors. N-acetylcysteine (NAC), a cystine pro-drug, increases the activity of the cystine-glutamate antiporter syst...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697766/ https://ncbi.nlm.nih.gov/pubmed/22903390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2837-3 |
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