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Metabolism of Peptide Reporters in Cell Lysates and Single Cells

The stability of an Abl kinase substrate peptide in a cytosolic lysate and in single cells was characterized. In the cytosolic lysate, the starting peptide was metabolized at an average initial rate of 1.7 ± 0.3 zmol pg(−;1) s(−;1) with a t(1/2) of 1.3 min. Five different fragments formed over time;...

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Hlavní autoři: Proctor, Angela, Wang, Qunzhao, Lawrence, David S., Allbritton, Nancy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697743/
https://ncbi.nlm.nih.gov/pubmed/22314840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2an16162a
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