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Transfer of nonselectable genes into mouse teratocarcinoma cells and transcription of the transferred human beta-globin gene.

Teratocarcinoma (TCC) stem cells can function as vehicles for the introduction of specific recombinant genes into mice. Because most genes do not code for a selectable marker, we investigated the transformation efficiency of vectors with a linked selectable gene. In one series, TCC cells first selec...

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Bibliographic Details
Main Authors: Wagner, E F, Mintz, B
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC369772/
https://ncbi.nlm.nih.gov/pubmed/6287228
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