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Design of retrovirus vectors for transfer and expression of the human beta-globin gene.

Regulated expression of the human beta-globin gene has been demonstrated in cultured murine erythroleukemia cells and in mice after retrovirus-mediated gene transfer. However, the low titer of recombinant viruses described to date results in relatively inefficient gene transfer, which limits their u...

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Autors principals: Miller, A D, Bender, M A, Harris, E A, Kaleko, M, Gelinas, R E
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253869/
https://ncbi.nlm.nih.gov/pubmed/3172343
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